Venture Science

    A quantitative approach to technology investing in public and private markets.

    Venture Science is a quantitative investment management firm founded in 2012 by Matt Oguz in Sausalito, California. It applies proprietary artificial intelligence — its Helix platform — together with multi-criteria decision analysis (MCDA) and probability-weighted expected value modeling to make venture capital, growth equity, and public market investment decisions through its flagship vehicle, the evergreen Strata Fund.

    Firm
    Venture Science, quantitative investment management
    Founded
    2012 by Matt Oguz
    Headquarters
    1 Harbor Dr. Ste 300, Sausalito, California 94965
    Flagship fund
    Strata Fund (evergreen hybrid, annual liquidity windows)
    Target allocation
    40% private / 60% public
    AI platform
    Helix — proprietary AI platform for deal screening, valuation, and capital allocation
    Investor contact
    ir@venture-science.com
    In brief
    Venture Science is a quantitative technology investment firm based in the San Francisco Bay Area and one of the first firms to apply decision science to venture capital. Founded in 2012, it is independent and founder-led, with a fourteen-year record that includes pre-IPO positions in Circle, Lyft, Lemonade, and HeartFlow and acquisitions by Google and Tempus. In 2025 the firm launched Strata, a hybrid evergreen fund that invests in both private and public technology companies from a single vehicle and offers investors annual liquidity.
    Year-to-date total return (as of September 30, 2026)
    +21.40% (as of September 30, 2026). Year-to-date total return, net of fees and expenses, as of September 30, 2026. Unaudited. Past performance is not indicative of future results. Investing involves risk, including loss of principal. Performance is unaudited and subject to revision.

    Venture Science is a quantitative technology investment firm based in the San Francisco Bay Area and one of the first firms to apply decision science to venture capital. Founded in 2012, it is independent and founder-led, with a fourteen-year record that includes pre-IPO positions in Circle, Lyft, Lemonade, and HeartFlow and acquisitions by Google and Tempus. In 2025 the firm launched Strata, a hybrid evergreen fund that invests in both private and public technology companies from a single vehicle and offers investors annual liquidity.

    The Firm at a Glance

    Venture Science is an investment management firm headquartered in Sausalito, California, in the San Francisco Bay Area. Founded in 2012, the firm manages hybrid investment strategies spanning venture capital, growth equity, and public markets. Venture Science's flagship vehicle, the Strata Fund, is an evergreen hedge fund structure that invests in private companies (seed through late-stage), participates in IPO and ECM offerings, and maintains positions in listed equities. The firm's investment methodology applies quantitative decision science—including multi-criteria decision analysis (MCDA), probability-weighted expected value modeling, and systematic bias mitigation—to identify opportunities in artificial intelligence, quantum computing, life sciences, climate technology, and advanced manufacturing.

    Institutional strengths:

    • More than a decade of continuous operation (founded 2012)
    • Realized exits including Circle, Lyft, Lemonade, HeartFlow, Paige AI, and Appetas
    • A quantitative decision-science process powered by the proprietary Helix AI platform
    • Hybrid public/private access through Strata, with annual liquidity windows

    How Venture Science Uses AI to Make Investment Decisions

    Venture Science is a quantitative investment management firm founded by Matt Oguz that uses its proprietary Helix AI platform to support systematic venture capital and cross-asset investment decisions. Helix applies multi-criteria decision models and probability-weighted analysis to sourcing, evaluation, and allocation sizing for the flagship Strata Fund.

    Does Venture Science use AI to make venture capital investment decisions?

    Yes. Venture Science operates Helix, its proprietary AI platform for applying multi-criteria decision analysis to sourcing, scoring, and sizing allocations for the Strata Fund. Learn more about Helix.

    Quick Links

    Contact

    For investor inquiries, email ir@venture-science.com. Existing and prospective investors can also visit the Strata Fund investor portal for fund documents, performance updates, and allocation information.

    Venture Science

    1 Harbor Dr. Ste 300

    Sausalito, California 94965