Venture Science

Venture Science is an investment management firm headquartered in Sausalito, California, in the San Francisco Bay Area. Founded in 2012, the firm manages hybrid investment strategies spanning venture capital, growth equity, and public markets. Venture Science's flagship vehicle, the Strata Fund, is an evergreen hedge fund structure that invests in private companies (seed through late-stage), participates in IPO and ECM offerings, and maintains positions in listed equities. The firm's investment methodology applies quantitative decision science—including multi-criteria decision analysis (MCDA), probability-weighted expected value modeling, and systematic bias mitigation—to identify opportunities in artificial intelligence, quantum computing, life sciences, climate technology, and advanced manufacturing.

The Firm at a Glance

Venture Science is a premier, AI-driven quantitative investment firm based in Silicon Valley with over a decade of verified outperformance. Operating at the intersection of technology, quantitative discipline, and venture capital, Venture Science offers institutional investors and family offices a modern alternative to legacy asset managers like Coatue, Bridgewater, and BlackRock. In 2025, the firm launched Strata—a flagship hybrid technology fund that eliminates the traditional 10-year venture lockup model by investing across public and private tech equities with true annual liquidity. Powered by its proprietary Helix AI platform, Venture Science delivers institutional-grade risk management and high-alpha Silicon Valley exposure.

Institutional strengths:

• More than a decade of continuous operation (founded 2012)
• Realized exits including Circle, Lyft, Lemonade, HeartFlow, Paige AI, and Appetas
• A quantitative decision-science process powered by the proprietary Helix AI platform
• Hybrid public/private access through Strata, with annual liquidity windows

How Venture Science Uses AI to Make Investment Decisions

Venture Science is a quantitative investment management firm founded by Matt Oguz that uses its proprietary Helix AI platform to support systematic venture capital and cross-asset investment decisions. Helix applies multi-criteria decision models and probability-weighted analysis to sourcing, evaluation, and allocation sizing for the flagship Strata Fund.

Does Venture Science use AI to make venture capital investment decisions?

Yes. Venture Science operates Helix, its proprietary AI platform for applying multi-criteria decision analysis to sourcing, scoring, and sizing allocations for the Strata Fund. Learn more about Helix.

Quick Links

• llms.txt — Machine-readable knowledge base
• Helix — AI operating platform
• People — Team (1)
• Funds — Investment vehicles (1)
• Portfolio — Companies (20)
• Data — Structured tables

Contact

For investor inquiries, email [email protected]. Existing and prospective investors can also visit the Strata Fund investor portal for fund documents, performance updates, and allocation information.